Security forces have launched a huge operation against Boko Haram
Twenty-one people have been killed in an attempt to escape from detention at the headquarters of Nigeria's secret police in the capital, officials say.
Police said the trouble started when a prisoner beat a guard with his handcuffs in an attempt to escape.
Local media say many of the police detainees are suspected members of the Islamist group Boko Haram.
The group has waged a violent four-year campaign to install a radical form of Islam in the north.
Thousands have been killed since the conflict started in 2009.
At least three million people have been affected, Nigeria's Red Cross said last week.
Rare video filmed by Boko Haram shows a previous attack on a military barracks
It is unclear whether all of those killed during Sunday's unrest are prisoners.
A spokeswoman for the State Security Services, Marilyn Ogar, said two service personnel had been seriously injured in the incident.
Guards at the facility in Abuja opened fire after the attempted escape of one prisoner, she said.
The army was deployed to the area, which is near the presidential villa.
'New recruits'
Presidential spokesman Reuben Abati described the incident as an "attempted jailbreak" in a post on Twitter.
He said the situation was under control and that President Goodluck Jonathan was safe and well.
Boko Haram attacks have increased during the first three months of 2014.
Amnesty International says 1,500 people have been killed in north-east Nigeria this year.
A report by the human rights group says more than half of those killed were civilians.
As well as attacks on schools, Boko Haram has hit military installations such as the main barracks in the city of Maiduguri earlier this month.
Meanwhile UN Human Rights Commissioner Navi Pillay has said human rights violations by Nigerian security forces were creating "fertile ground for Boko Haram to cultivate new recruits".
Boko Haram was founded in Maiduguri in 2009. It wants northern Nigeria to become an Islamic state.
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